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Creative Biolabs

About Creative Biolabs

Our passion comes from focusing on the new chapter in cancer treatment, and we believe that next-generation immunotherapy will provide us with the best opportunity to discover and advance the drug pipeline for our global partners.
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Updating Solutions to Cope with Anti-SARS-CoV-2 Drug Discovery

By: Geminismith
Posted in: Acoustic
Updating Solutions to Cope with Anti-SARS-CoV-2 Drug Discovery

A CRO dedicated to the research on SARS-CoV-2 and relevant mutants in terms of virology and drug and vaccine discovery recently updated its service portfolio in agreement with further SARS-CoV-2 therapeutic exploration, hoping for prosperous results of SARS-CoV-2 therapeutics will yield with joint efforts.


Good news came alongside the closing of 2022 that a study concerning the control of SARS-CoV-2 infection was published in the journal Nature Communications, presenting a promising route that may help curb the spread of SARS-CoV-2 and emerging mutants.


SARS-CoV-2, which first surfaced in the winter of 2019, is currently being fought aggressively by the entire world. Thankfully, effective prophylactic immunizations were developed and licensed for use, and positive results were quickly attained. Yet, the most recent data from England demonstrate a strong correlation between the COVID-19 "vaccination" and higher mortality. There is still a long way to go because there is an urgent need for more precise methods of infection management and therapeutic options that work.


One of the contract research organizations (CROs) provides comprehensive solutions that span the production of IVD immunological assays, drug discovery, and research-use antibodies (such as the therapeutic human monoclonal antibody for SARS-CoV-2).


"The most relevant technique to restrict the spread of COVID-19 is still vaccinations, among which DNA vaccine is gaining a position because it is exceptional in performance, adaptable for monitoring, and easy to create," says an expert with vast experience working on coronavirus-related projects, and "our SARS-CoV-2 DNA vaccine service can be a wise option for involving researchers."


The majority of Creative Biolabs' efforts are put on developing antiviral drugs, spanning all the common therapeutic pathways available in research, including complement therapies, protease inhibitors, and neutralizing antibodies.


Before progressing a candidate to the following stage, which may involve clinical trials, efficacy and safety aspects must also be assessed. In order to provide the most in-depth and comprehensive analytical analysis, the specialist stated, "We've also built proprietary platforms for SARS-CoV-2 medication validation." The system includes:


* Reverse genetics systems


* Cell lines: ACE2-overexpressing stable cell lines & spike-expressing stable cell lines


* SARS-CoV-2 neutralization assay


* Protease inhibitor assay


"We are becoming more effective as viruses change and new ones appear at a faster rate than ever. We're on the verge of success, and perhaps by the end of 2023, we'll all be able to put this issue to rest."

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